Application:

Luc-B.cereus Na is used as ProLuciferinBacillus cereus is a rod-shaped beta hemolytic bacterium commonly found in food and soil. Some strains can be associated with food intoxications, mainly from raw meat and poultry products. One example is the so called “fried rice syndrome”, that occurs when dishes containing cooked rice are left for several hours at room temperature. Typical symptoms of the infection include severe nausea, vomiting and diarrhea. Some strains of Bacillus cereus on the contrary are not harmful at all and they are used as probiotics food additives in animal farming to reduce the presence of other pathogens like Salmonella in the cecum end intestine. Bacillus cereus expresses phosphatidyl-choline specific phospholipase C (PC-PLC), encoded by the plc gene, which is regulated by PlcR. In addition, the expression of PlcR is dependent on the growth medium. Luc-B.cereus Na (L-8275) is a synthetic chemiluminescent substrate for the phosphatidyl-choline specific phospholipase C. The enzyme cleaves off phosphocholine from L-8275, leading to the release of D-Luc, and consequent strong light emission B. cereus culture exhibited strong luminescence, while RLU values were much lower for samples with B. thuringiensis.

BIOSYNTH Carbosynth ®  是在精细化学品市场的两个关键球员合并后成立新的全球品牌。我们提供了一系列令人印象深刻的特种化学品，而且化学对我们来说也不难 –如果我们没有化合物，我们一定会成功！我们足够大，可以在全球范围内思考和采取行动，而又足够小，可以灵活和创新。 

我们很大 –我们是制药，生命科学，食品，农业化学，化妆品和诊断领域许多机构的首选供应商。我们制造和采购各种化学和生化产品，并专门从事碳水化合物，核苷，抗微生物剂，API，酶底物和天然产品的生产。我们的工厂位于三大洲，在瑞士，英国，斯洛伐克和中国设有制造实验室，并在美国设有分销中心。我们的研发资源和生产设施现代化且用途广泛，使我们能够生产毫克到吨级的化学品。

我们很小 –我们以精益，敏捷的管理和快速的沟通渠道组成小型团队。我们非常灵活，可以快速有效地响应客户和市场需求。

我们具有创新精神 -我们喜欢开发新产品，并与客户和产品专家保持密切关系。雄心勃勃的研发计划是我们文化的核心，我们的研究已经产生了令人印象深刻的知识产权组合，例如我们的新型化学发光AquaSpark®产品系列。

我们是化学专家 - 定制合成是我们业务的快速增长部分。我们在酶底物，有机合成的基础模块以及碳水化合物和核苷化学方面拥有业内顶尖的专业知识。此外，质量是我们的绝对优先考虑，我们按照ISO和GMP质量标准运作。